The IRX1/HOXA connection: insights into a novel t(4;11)- specific cancer mechanism

One hallmark of MLL-r leukemia is the highly specific gene expression signature indicative for commonly deregulated target genes. An usual read-out for this transcriptional deregulation is the HOXA gene cluster, where upregulated HOXA genes are detected in MLL-r AML and ALL patients. In case of t(4;...

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Detalles Bibliográficos
Autores principales: Kühn, Alessa, Löscher, Denise, Marschalek, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085233/
https://www.ncbi.nlm.nih.gov/pubmed/27175594
http://dx.doi.org/10.18632/oncotarget.9241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085233/
https://www.ncbi.nlm.nih.gov/pubmed/27175594
http://dx.doi.org/10.18632/oncotarget.9241

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