Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice

Pulmonary neuroepithelial bodies (NEBs), presumed polymodal airway sensors, consist of innervated clusters of amine (serotonin) and peptide-producing cells. While NEB responses to acute hypoxia are mediated by a membrane-bound O(2) sensor complex, responses to sustained and/or chronic hypoxia involv...

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Detalles Bibliográficos
Autores principales: Pan, Jie, Bishop, Tammie, Ratcliffe, Peter J, Yeger, Herman, Cutz, Ernest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085281/
https://www.ncbi.nlm.nih.gov/pubmed/27800509
http://dx.doi.org/10.2147/HP.S103957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085281/
https://www.ncbi.nlm.nih.gov/pubmed/27800509
http://dx.doi.org/10.2147/HP.S103957

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