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Hyperplasia and hypertrophy of pulmonary neuroepithelial bodies, presumed airway hypoxia sensors, in hypoxia-inducible factor prolyl hydroxylase-deficient mice

Pulmonary neuroepithelial bodies (NEBs), presumed polymodal airway sensors, consist of innervated clusters of amine (serotonin) and peptide-producing cells. While NEB responses to acute hypoxia are mediated by a membrane-bound O(2) sensor complex, responses to sustained and/or chronic hypoxia involv...

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Detalles Bibliográficos
Autores principales:	Pan, Jie, Bishop, Tammie, Ratcliffe, Peter J, Yeger, Herman, Cutz, Ernest
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085281/ https://www.ncbi.nlm.nih.gov/pubmed/27800509 http://dx.doi.org/10.2147/HP.S103957

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