High-dose irradiation in combination with toll-like receptor 9 agonist CpG oligodeoxynucleotide 7909 downregulates PD-L1 expression via the NF-κB signaling pathway in non-small cell lung cancer cells

OBJECTIVES: Irradiation resistance appears as local recurrence and distant metastasis in advanced stages of non-small cell lung cancer (NSCLC). High-dose irradiation combined with immunotherapy improved overall survival and local control of NSCLC. This study explored the underlying molecular mechani...

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Detalles Bibliográficos
Autores principales: Chen, Xue, Zhang, Qi, Luo, Youjun, Gao, Caixia, Zhuang, Xibing, Xu, Guoxiong, Qiao, Tiankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085295/
https://www.ncbi.nlm.nih.gov/pubmed/27799798
http://dx.doi.org/10.2147/OTT.S116629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085295/
https://www.ncbi.nlm.nih.gov/pubmed/27799798
http://dx.doi.org/10.2147/OTT.S116629

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