Inducing G2/M Cell Cycle Arrest and Apoptosis through Generation Reactive Oxygen Species (ROS)-Mediated Mitochondria Pathway in HT-29 Cells by Dentatin (DEN) and Dentatin Incorporated in Hydroxypropyl-β-Cyclodextrin (DEN-HPβCD)

Dentatin (DEN), purified from the roots of Clausena excavata Burm f., has poor aqueous solubility that reduces its therapeutic application. The aim of this study was to assess the effects of DEN-HPβCD (hydroxypropyl-β-cyclodextrin) complex as an anticancer agent in HT29 cancer cell line and compare...

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Detalles Bibliográficos
Autores principales: Ashwaq, Al-Abboodi Shakir, Al-Qubaisi, Mothanna Sadiq, Rasedee, Abdullah, Abdul, Ahmad Bustamam, Taufiq-Yap, Yun Hin, Yeap, Swee Keong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085686/
https://www.ncbi.nlm.nih.gov/pubmed/27763535
http://dx.doi.org/10.3390/ijms17101653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085686/
https://www.ncbi.nlm.nih.gov/pubmed/27763535
http://dx.doi.org/10.3390/ijms17101653

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