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Porcine Zygote Injection with Cas9/sgRNA Results in DMD-Modified Pig with Muscle Dystrophy

Dystrophinopathy, including Duchenne muscle dystrophy (DMD) and Becker muscle dystrophy (BMD) is an incurable X-linked hereditary muscle dystrophy caused by a mutation in the DMD gene in coding dystrophin. Advances in further understanding DMD/BMD for therapy are expected. Studies on mdx mice and do...

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Detalles Bibliográficos
Autores principales: Yu, Hong-Hao, Zhao, Heng, Qing, Yu-Bo, Pan, Wei-Rong, Jia, Bao-Yu, Zhao, Hong-Ye, Huang, Xing-Xu, Wei, Hong-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085701/
https://www.ncbi.nlm.nih.gov/pubmed/27735844
http://dx.doi.org/10.3390/ijms17101668