Modulation of Compartmentalised Cyclic Nucleotide Signalling via Local Inhibition of Phosphodiesterase Activity

Cyclic nucleotide phosphodiesterases (PDEs) are the only enzymes that degrade the cyclic nucleotides cAMP and cGMP, and play a key role in modulating the amplitude and duration of the signal delivered by these two key intracellular second messengers. Defects in cyclic nucleotide signalling are known...

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Detalles Bibliográficos
Autores principales: Brescia, Marcella, Zaccolo, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085705/
https://www.ncbi.nlm.nih.gov/pubmed/27706091
http://dx.doi.org/10.3390/ijms17101672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085705/
https://www.ncbi.nlm.nih.gov/pubmed/27706091
http://dx.doi.org/10.3390/ijms17101672

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