Doxorubicin Regulates Autophagy Signals via Accumulation of Cytosolic Ca(2+) in Human Cardiac Progenitor Cells

Doxorubicin (DOXO) is widely used to treat solid tumors. However, its clinical use is limited by side effects including serious cardiotoxicity due to cardiomyocyte damage. Resident cardiac progenitor cells (hCPCs) act as key regulators of homeostasis in myocardial cells. However, little is known abo...

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Detalles Bibliográficos
Autores principales: Park, Ji Hye, Choi, Sung Hyun, Kim, Hyungtae, Ji, Seung Taek, Jang, Woong Bi, Kim, Jae Ho, Baek, Sang Hong, Kwon, Sang Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085713/
https://www.ncbi.nlm.nih.gov/pubmed/27735842
http://dx.doi.org/10.3390/ijms17101680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085713/
https://www.ncbi.nlm.nih.gov/pubmed/27735842
http://dx.doi.org/10.3390/ijms17101680

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