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Doxorubicin Regulates Autophagy Signals via Accumulation of Cytosolic Ca(2+) in Human Cardiac Progenitor Cells
Doxorubicin (DOXO) is widely used to treat solid tumors. However, its clinical use is limited by side effects including serious cardiotoxicity due to cardiomyocyte damage. Resident cardiac progenitor cells (hCPCs) act as key regulators of homeostasis in myocardial cells. However, little is known abo...
Autores principales: | Park, Ji Hye, Choi, Sung Hyun, Kim, Hyungtae, Ji, Seung Taek, Jang, Woong Bi, Kim, Jae Ho, Baek, Sang Hong, Kwon, Sang Mo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085713/ https://www.ncbi.nlm.nih.gov/pubmed/27735842 http://dx.doi.org/10.3390/ijms17101680 |
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