Methionine Regulates mTORC1 via the T1R1/T1R3-PLCβ-Ca(2+)-ERK1/2 Signal Transduction Process in C2C12 Cells

The mammalian target of rapamycin complex 1 (mTORC1) integrates amino acid (AA) availability to support protein synthesis and cell growth. Taste receptor type 1 member (T1R) is a G protein-coupled receptor that functions as a direct sensor of extracellular AA availability to regulate mTORC1 through...

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Detalles Bibliográficos
Autores principales: Zhou, Yuanfei, Ren, Jiao, Song, Tongxing, Peng, Jian, Wei, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085716/
https://www.ncbi.nlm.nih.gov/pubmed/27727170
http://dx.doi.org/10.3390/ijms17101684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085716/
https://www.ncbi.nlm.nih.gov/pubmed/27727170
http://dx.doi.org/10.3390/ijms17101684

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