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Methionine Regulates mTORC1 via the T1R1/T1R3-PLCβ-Ca(2+)-ERK1/2 Signal Transduction Process in C2C12 Cells

The mammalian target of rapamycin complex 1 (mTORC1) integrates amino acid (AA) availability to support protein synthesis and cell growth. Taste receptor type 1 member (T1R) is a G protein-coupled receptor that functions as a direct sensor of extracellular AA availability to regulate mTORC1 through...

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Detalles Bibliográficos
Autores principales:	Zhou, Yuanfei, Ren, Jiao, Song, Tongxing, Peng, Jian, Wei, Hongkui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085716/ https://www.ncbi.nlm.nih.gov/pubmed/27727170 http://dx.doi.org/10.3390/ijms17101684

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