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Age- and Brain Region-Specific Changes of Glucose Metabolic Disorder, Learning, and Memory Dysfunction in Early Alzheimer’s Disease Assessed in APP/PS1 Transgenic Mice Using (18)F-FDG-PET

Alzheimer’s disease (AD) is a leading cause of dementia worldwide, associated with cognitive deficits and brain glucose metabolic alteration. However, the associations of glucose metabolic changes with cognitive dysfunction are less detailed. Here, we examined the brains of APP/presenilin 1 (PS1) tr...

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Detalles Bibliográficos
Autores principales: Li, Xue-Yuan, Men, Wei-Wei, Zhu, Hua, Lei, Jian-Feng, Zuo, Fu-Xing, Wang, Zhan-Jing, Zhu, Zhao-Hui, Bao, Xin-Jie, Wang, Ren-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085739/
https://www.ncbi.nlm.nih.gov/pubmed/27763550
http://dx.doi.org/10.3390/ijms17101707