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Age- and Brain Region-Specific Changes of Glucose Metabolic Disorder, Learning, and Memory Dysfunction in Early Alzheimer’s Disease Assessed in APP/PS1 Transgenic Mice Using (18)F-FDG-PET
Alzheimer’s disease (AD) is a leading cause of dementia worldwide, associated with cognitive deficits and brain glucose metabolic alteration. However, the associations of glucose metabolic changes with cognitive dysfunction are less detailed. Here, we examined the brains of APP/presenilin 1 (PS1) tr...
Autores principales: | Li, Xue-Yuan, Men, Wei-Wei, Zhu, Hua, Lei, Jian-Feng, Zuo, Fu-Xing, Wang, Zhan-Jing, Zhu, Zhao-Hui, Bao, Xin-Jie, Wang, Ren-Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085739/ https://www.ncbi.nlm.nih.gov/pubmed/27763550 http://dx.doi.org/10.3390/ijms17101707 |
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