Assessment of Amino Acid/Drug Transporters for Renal Transport of [(18)F]Fluciclovine (anti-[(18)F]FACBC) in Vitro

[(18)F]Fluciclovine (trans-1-amino-3-[(18)F]fluorocyclobutanecarboxylic acid; anti-[(18)F]FACBC), a positron emission tomography tracer used for the diagnosis of recurrent prostate cancer, is transported via amino acid transporters (AATs) with high affinity (K(m): 97–230 μM). However, the mechanism...

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Detalles Bibliográficos
Autores principales: Ono, Masahiro, Baden, Atsumi, Okudaira, Hiroyuki, Kobayashi, Masato, Kawai, Keiichi, Oka, Shuntaro, Yoshimura, Hirokatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085761/
https://www.ncbi.nlm.nih.gov/pubmed/27754421
http://dx.doi.org/10.3390/ijms17101730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085761/
https://www.ncbi.nlm.nih.gov/pubmed/27754421
http://dx.doi.org/10.3390/ijms17101730

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