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Decreased Poly(ADP-Ribose) Polymerase 1 Expression Attenuates Glucose Oxidase-Induced Damage in Rat Cochlear Marginal Strial Cells

Oxidative damage to the inner ear is responsible for several types of sensorineural deafness. Cochlear stria marginal cells (MCs) are thought to be vulnerable to such oxidative stress. Activated poly(ADP-ribose) polymerase 1 (PARP1) has been implicated in several diseases, but the effect of PARP1 on...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanyuan, Yang, Yang, Xie, Zhen, Zuo, Wenqi, Jiang, Hongyan, Zhao, Xueyan, Sun, Yu, Kong, Weijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085996/
https://www.ncbi.nlm.nih.gov/pubmed/26526840
http://dx.doi.org/10.1007/s12035-015-9469-7