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Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology
Human prion diseases are fatal neurodegenerative disorders with a genetic, sporadic or infectiously acquired aetiology. Neuropathologically, human prion diseases are characterized by deposition of misfolded prion protein and neuronal loss. In post-mortem brain tissue from patients with other neurode...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086055/ https://www.ncbi.nlm.nih.gov/pubmed/27793194 http://dx.doi.org/10.1186/s40478-016-0383-7 |