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Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology

Human prion diseases are fatal neurodegenerative disorders with a genetic, sporadic or infectiously acquired aetiology. Neuropathologically, human prion diseases are characterized by deposition of misfolded prion protein and neuronal loss. In post-mortem brain tissue from patients with other neurode...

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Detalles Bibliográficos
Autores principales:	Wiersma, Vera I., van Hecke, Wim, Scheper, Wiep, van Osch, Martijn A. J., Hermsen, Will J. M., Rozemuller, Annemieke J. M., Hoozemans, Jeroen J. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086055/ https://www.ncbi.nlm.nih.gov/pubmed/27793194 http://dx.doi.org/10.1186/s40478-016-0383-7

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