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Enhanced therapeutic efficacy of LHRHa-targeted brucea javanica oil liposomes for ovarian cancer

BACKGROUND: Although brucea javanica oil liposomes (BJOLs) have been used clinically to treat ovarian cancer, its clinical efficacy is often limited by systemic side effects due to non-specific distribution. Luteinizing hormone releasing hormone receptor (LHRHR) is overexpressed in most ovarian canc...

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Detalles Bibliográficos
Autores principales: Ye, Hongxia, Liu, Xiaojuan, Sun, Jiangchuan, Zhu, Shenyin, Zhu, Yi, Chang, Shufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086058/
https://www.ncbi.nlm.nih.gov/pubmed/27793127
http://dx.doi.org/10.1186/s12885-016-2870-4