Severe respiratory changes at end stage in a FUS-induced disease state in adult rats

BACKGROUND: Fused in sarcoma (FUS) is an RNA-binding protein associated with the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration. ALS manifests in patients as a progressive paralysis which leads to respiratory dysfunction and failure, the primary...

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Detalles Bibliográficos
Autores principales: Jackson, Kasey L., Dhaibar, Hemangini A., Dayton, Robert D., Cananzi, Sergio G., Mayhan, William G., Glasscock, Edward, Klein, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086065/
https://www.ncbi.nlm.nih.gov/pubmed/27793099
http://dx.doi.org/10.1186/s12868-016-0304-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086065/
https://www.ncbi.nlm.nih.gov/pubmed/27793099
http://dx.doi.org/10.1186/s12868-016-0304-5

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