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Severe respiratory changes at end stage in a FUS-induced disease state in adult rats
BACKGROUND: Fused in sarcoma (FUS) is an RNA-binding protein associated with the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration. ALS manifests in patients as a progressive paralysis which leads to respiratory dysfunction and failure, the primary...
Autores principales: | Jackson, Kasey L., Dhaibar, Hemangini A., Dayton, Robert D., Cananzi, Sergio G., Mayhan, William G., Glasscock, Edward, Klein, Ronald L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086065/ https://www.ncbi.nlm.nih.gov/pubmed/27793099 http://dx.doi.org/10.1186/s12868-016-0304-5 |
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