PTEN Inhibits Cell Proliferation, Promotes Cell Apoptosis, and Induces Cell Cycle Arrest via Downregulating the PI3K/AKT/hTERT Pathway in Lung Adenocarcinoma A549 Cells

PTEN plays an essential role in tumorigenesis and both its mutation and inactivation can influence proliferation, apoptosis, and cell cycle progression in tumor cells. However, the precise role of PTEN in lung cancer cells has not been well studied. To address this, we have generated lung adenocarci...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Xiao-Xiao, Cao, Lan-Yu, Chen, Xi, Xiao, Jian, Zou, Yong, Chen, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086351/
https://www.ncbi.nlm.nih.gov/pubmed/27822469
http://dx.doi.org/10.1155/2016/2476842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086351/
https://www.ncbi.nlm.nih.gov/pubmed/27822469
http://dx.doi.org/10.1155/2016/2476842

Ejemplares similares