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RANTES Gene Polymorphisms Associated with HIV-1 Infections in Kenyan Population

Previous studies have reported that two single nucleotide polymorphisms (SNPs) in the RANTES gene promoter region, -403G/A and -28C/G, are associated with a slower rate of decline in CD4+ T cell count. In addition, as a ligand of the major HIV coreceptor CCR5, it is known to block HIV-CCR5 interacti...

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Detalles Bibliográficos
Autores principales: Mutuiri, Shem P. M., Kutima, Helen L., Mwapagha, Lamech M., Munyao, James K., Nyamache, Anthony Kebira, Wanjiru, Irene, Khamadi, Samoel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086385/
https://www.ncbi.nlm.nih.gov/pubmed/27821902
http://dx.doi.org/10.1155/2016/4703854