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Membrane-bound p35 Subunit of IL-12 on Tumor Cells is Functionally Equivalent to Membrane-bound Heterodimeric Single Chain IL-12 for Induction of Anti-tumor Immunity

In this study, we compared two different tumor cell vaccines for their induction of anti-tumor immunity; one was a tumor cell clone expressing a membrane-bound form of IL-12 p35 subunit (mbIL-12 p35 tumor clone), and the other was a tumor clone expressing heterodimeric IL-12 as a single chain (mb-sc...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Jin, Park, Sang Min, Lee, Hayyoung, Kim, Young Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086455/
https://www.ncbi.nlm.nih.gov/pubmed/27799876
http://dx.doi.org/10.4110/in.2016.16.5.305