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Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice

Glucocorticoid (Gc) excess, from endogenous overproduction in disorders of the hypothalamic-pituitary-adrenal axis or exogenous medical therapy, is recognized to cause adverse metabolic side effects. The Gc receptor (GR) is widely expressed throughout the body, including brain regions such as the hy...

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Detalles Bibliográficos
Autores principales: Sefton, Charlotte, Harno, Erika, Davies, Alison, Small, Helen, Allen, Tiffany-Jayne, Wray, Jonathan R., Lawrence, Catherine B., Coll, Anthony P., White, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086535/
https://www.ncbi.nlm.nih.gov/pubmed/27649090
http://dx.doi.org/10.1210/en.2016-1571