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Elevated Hypothalamic Glucocorticoid Levels Are Associated With Obesity and Hyperphagia in Male Mice
Glucocorticoid (Gc) excess, from endogenous overproduction in disorders of the hypothalamic-pituitary-adrenal axis or exogenous medical therapy, is recognized to cause adverse metabolic side effects. The Gc receptor (GR) is widely expressed throughout the body, including brain regions such as the hy...
Autores principales: | Sefton, Charlotte, Harno, Erika, Davies, Alison, Small, Helen, Allen, Tiffany-Jayne, Wray, Jonathan R., Lawrence, Catherine B., Coll, Anthony P., White, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086535/ https://www.ncbi.nlm.nih.gov/pubmed/27649090 http://dx.doi.org/10.1210/en.2016-1571 |
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