Structural Maturation of HIV-1 Reverse Transcriptase—A Metamorphic Solution to Genomic Instability

Human immunodeficiency virus 1 (HIV-1) reverse transcriptase (RT)—a critical enzyme of the viral life cycle—undergoes a complex maturation process, required so that a pair of p66 precursor proteins can develop conformationally along different pathways, one evolving to form active polymerase and ribo...

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Detalles Bibliográficos
Autor principal: London, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086598/
https://www.ncbi.nlm.nih.gov/pubmed/27690082
http://dx.doi.org/10.3390/v8100260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086598/
https://www.ncbi.nlm.nih.gov/pubmed/27690082
http://dx.doi.org/10.3390/v8100260

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