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Hepatitis B Virus Protein X Induces Degradation of Talin-1

In the infected human hepatocyte, expression of the hepatitis B virus (HBV) accessory protein X (HBx) is essential to maintain viral replication in vivo. HBx critically interacts with the host damaged DNA binding protein 1 (DDB1) and the associated ubiquitin ligase machinery, suggesting that HBx fun...

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Detalles Bibliográficos
Autores principales: van de Klundert, Maarten A. A., van den Biggelaar, Maartje, Kootstra, Neeltje A., Zaaijer, Hans L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086613/
https://www.ncbi.nlm.nih.gov/pubmed/27775586
http://dx.doi.org/10.3390/v8100281