Single Amino Acid Substitution N659D in HIV-2 Envelope Glycoprotein (Env) Impairs Viral Release and Hampers BST-2 Antagonism

BST-2 or tetherin is a host cell restriction factor that prevents the budding of enveloped viruses at the cell surface, thus impairing the viral spread. Several countermeasures to evade this antiviral factor have been positively selected in retroviruses: the human immunodeficiency virus type 2 (HIV-...

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Detalles Bibliográficos
Autores principales: Dufrasne, François E., Lombard, Catherine, Goubau, Patrick, Ruelle, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086617/
https://www.ncbi.nlm.nih.gov/pubmed/27754450
http://dx.doi.org/10.3390/v8100285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086617/
https://www.ncbi.nlm.nih.gov/pubmed/27754450
http://dx.doi.org/10.3390/v8100285

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