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4EBP-Dependent Signaling Supports West Nile Virus Growth and Protein Expression

West Nile virus (WNV) is a (+) sense, single-stranded RNA virus in the Flavivirus genus. WNV RNA possesses an (m7)GpppN(m) 5′ cap with 2′-O-methylation that mimics host mRNAs preventing innate immune detection and allowing the virus to translate its RNA genome through the utilization of cap-dependen...

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Detalles Bibliográficos
Autores principales: Shives, Katherine D., Massey, Aaron R., May, Nicholas A., Morrison, Thomas E., Beckham, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086619/
https://www.ncbi.nlm.nih.gov/pubmed/27763553
http://dx.doi.org/10.3390/v8100287