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4EBP-Dependent Signaling Supports West Nile Virus Growth and Protein Expression
West Nile virus (WNV) is a (+) sense, single-stranded RNA virus in the Flavivirus genus. WNV RNA possesses an (m7)GpppN(m) 5′ cap with 2′-O-methylation that mimics host mRNAs preventing innate immune detection and allowing the virus to translate its RNA genome through the utilization of cap-dependen...
Autores principales: | Shives, Katherine D., Massey, Aaron R., May, Nicholas A., Morrison, Thomas E., Beckham, J. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086619/ https://www.ncbi.nlm.nih.gov/pubmed/27763553 http://dx.doi.org/10.3390/v8100287 |
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