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Glypican-3 Targeting Immunotoxins for the Treatment of Liver Cancer

Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer, yet no effective therapeutics exist. This review provides an overview of the recent development of recombinant immunotoxins for the treatment of glypican-3 (GPC3) expressing HCC. GPC3 is a cell surface heparan sulfate pr...

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Detalles Bibliográficos
Autores principales: Fleming, Bryan D., Ho, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086635/
https://www.ncbi.nlm.nih.gov/pubmed/27669301
http://dx.doi.org/10.3390/toxins8100274