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Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins

Botulinum neurotoxins are bacterial proteins that cause botulism, a life-threatening disease. Therapy relies mostly on post-intoxication antibody treatment. The only accepted method to measure the potency of, and to approve, antitoxin preparations is the mouse lethality neutralization bioassay. Howe...

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Detalles Bibliográficos
Autores principales: Rosen, Osnat, Ozeri, Eyal, Barnea, Ada, David, Alon Ben, Zichel, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086636/
https://www.ncbi.nlm.nih.gov/pubmed/27669303
http://dx.doi.org/10.3390/toxins8100276