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Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins
Botulinum neurotoxins are bacterial proteins that cause botulism, a life-threatening disease. Therapy relies mostly on post-intoxication antibody treatment. The only accepted method to measure the potency of, and to approve, antitoxin preparations is the mouse lethality neutralization bioassay. Howe...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086636/ https://www.ncbi.nlm.nih.gov/pubmed/27669303 http://dx.doi.org/10.3390/toxins8100276 |