Pertussis Toxin Exploits Host Cell Signaling Pathways Induced by Meningitis-Causing E. coli K1-RS218 and Enhances Adherence of Monocytic THP-1 Cells to Human Cerebral Endothelial Cells

Pertussis toxin (PTx), the major virulence factor of the whooping cough-causing bacterial pathogen Bordetella pertussis, permeabilizes the blood–brain barrier (BBB) in vitro and in vivo. Breaking barriers might promote translocation of meningitis-causing bacteria across the BBB, thereby facilitating...

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Detalles Bibliográficos
Autores principales: Starost, Laura Julia, Karassek, Sascha, Sano, Yasuteru, Kanda, Takashi, Kim, Kwang Sik, Dobrindt, Ulrich, Rüter, Christian, Schmidt, Marcus Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086651/
https://www.ncbi.nlm.nih.gov/pubmed/27754355
http://dx.doi.org/10.3390/toxins8100291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086651/
https://www.ncbi.nlm.nih.gov/pubmed/27754355
http://dx.doi.org/10.3390/toxins8100291

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