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Novel Catalytically-Inactive PII Metalloproteinases from a Viperid Snake Venom with Substitutions in the Canonical Zinc-Binding Motif
Snake venom metalloproteinases (SVMPs) play key biological roles in prey immobilization and digestion. The majority of these activities depend on the hydrolysis of relevant protein substrates in the tissues. Hereby, we describe several isoforms and a cDNA clone sequence, corresponding to PII SVMP ho...
Autores principales: | Camacho, Erika, Sanz, Libia, Escalante, Teresa, Pérez, Alicia, Villalta, Fabián, Lomonte, Bruno, Neves-Ferreira, Ana Gisele C., Feoli, Andrés, Calvete, Juan J., Gutiérrez, José María, Rucavado, Alexandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086652/ https://www.ncbi.nlm.nih.gov/pubmed/27754342 http://dx.doi.org/10.3390/toxins8100292 |
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