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Improvement of the Pharmacological Properties of Maize RIP by Cysteine-Specific PEGylation

To improve the pharmacological properties of maize ribosome-inactivating protein (maize RIP) for targeting HIV-infected cells, the previously engineered TAT-fused active form of maize RIP (MOD) was further engineered for cysteine-directed PEGylation. In this work, two potential antigenic sites, name...

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Detalles Bibliográficos
Autores principales: Au, Ka-Yee, Shi, Wei-Wei, Qian, Shuai, Zuo, Zhong, Shaw, Pang-Chui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086658/
https://www.ncbi.nlm.nih.gov/pubmed/27763506
http://dx.doi.org/10.3390/toxins8100298