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Improvement of the Pharmacological Properties of Maize RIP by Cysteine-Specific PEGylation
To improve the pharmacological properties of maize ribosome-inactivating protein (maize RIP) for targeting HIV-infected cells, the previously engineered TAT-fused active form of maize RIP (MOD) was further engineered for cysteine-directed PEGylation. In this work, two potential antigenic sites, name...
Autores principales: | Au, Ka-Yee, Shi, Wei-Wei, Qian, Shuai, Zuo, Zhong, Shaw, Pang-Chui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086658/ https://www.ncbi.nlm.nih.gov/pubmed/27763506 http://dx.doi.org/10.3390/toxins8100298 |
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