Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer’s disease-risk genes

Alzheimer’s disease (AD) is a circadian clock-related disease. However, it is not very clear whether pre-symptomatic AD leads to circadian disruption or whether malfunction of circadian rhythms exerts influence on development of AD. Here, we report a functional clock that exists in the hippocampus....

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Detalles Bibliográficos
Autores principales: Ma, Zhixiong, Jiang, Weiliang, Zhang, Eric Erquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086843/
https://www.ncbi.nlm.nih.gov/pubmed/27796320
http://dx.doi.org/10.1038/srep36035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086843/
https://www.ncbi.nlm.nih.gov/pubmed/27796320
http://dx.doi.org/10.1038/srep36035

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