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Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer’s disease-risk genes
Alzheimer’s disease (AD) is a circadian clock-related disease. However, it is not very clear whether pre-symptomatic AD leads to circadian disruption or whether malfunction of circadian rhythms exerts influence on development of AD. Here, we report a functional clock that exists in the hippocampus....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086843/ https://www.ncbi.nlm.nih.gov/pubmed/27796320 http://dx.doi.org/10.1038/srep36035 |