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A dual specificity kinase, DYRK1A, as a potential therapeutic target for head and neck squamous cell carcinoma

Despite advances in clinical management, 5-year survival rate in patients with late-stage head and neck squamous cell carcinoma (HNSCC) has not improved significantly over the past decade. Targeted therapies have emerged as one of the most promising approaches to treat several malignancies. Though t...

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Detalles Bibliográficos
Autores principales: Radhakrishnan, Aneesha, Nanjappa, Vishalakshi, Raja, Remya, Sathe, Gajanan, Puttamallesh, Vinuth N., Jain, Ankit P., Pinto, Sneha M., Balaji, Sai A., Chavan, Sandip, Sahasrabuddhe, Nandini A., Mathur, Premendu P., Kumar, Mahesh M., Prasad, T. S. Keshava, Santosh, Vani, Sukumar, Geethanjali, Califano, Joseph A., Rangarajan, Annapoorni, Sidransky, David, Pandey, Akhilesh, Gowda, Harsha, Chatterjee, Aditi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086852/
https://www.ncbi.nlm.nih.gov/pubmed/27796319
http://dx.doi.org/10.1038/srep36132