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Ductular reaction-on-a-chip: Microfluidic co-cultures to study stem cell fate selection during liver injury
Liver injury modulates local microenvironment, triggering production of signals that instruct stem cell fate choices. In this study, we employed a microfluidic co-culture system to recreate important interactions in the liver stem cell niche, those between adult hepatocytes and liver progenitor cell...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086854/ https://www.ncbi.nlm.nih.gov/pubmed/27796316 http://dx.doi.org/10.1038/srep36077 |