Cargando…

Glycosylation changes in the globular head of H3N2 influenza hemagglutinin modulate receptor binding without affecting virus virulence

Since the emergence of human H3N2 influenza A viruses in the pandemic of 1968, these viruses have become established as strains of moderate severity. A decline in virulence has been accompanied by glycan accumulation on the hemagglutinin globular head, and hemagglutinin receptor binding has changed...

Descripción completa

Detalles Bibliográficos
Autores principales: Alymova, Irina V., York, Ian A., Air, Gillian M., Cipollo, John F., Gulati, Shelly, Baranovich, Tatiana, Kumar, Amrita, Zeng, Hui, Gansebom, Shane, McCullers, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086918/
https://www.ncbi.nlm.nih.gov/pubmed/27796371
http://dx.doi.org/10.1038/srep36216