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Rawcopy: Improved copy number analysis with Affymetrix arrays

Microarray data is subject to noise and systematic variation that negatively affects the resolution of copy number analysis. We describe Rawcopy, an R package for processing of Affymetrix CytoScan HD, CytoScan 750k and SNP 6.0 microarray raw intensities (CEL files). Noise characteristics of a large...

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Detalles Bibliográficos
Autores principales: Mayrhofer, Markus, Viklund, Björn, Isaksson, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086940/
https://www.ncbi.nlm.nih.gov/pubmed/27796336
http://dx.doi.org/10.1038/srep36158