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lncRNA H19/miR-675 axis regulates cardiomyocyte apoptosis by targeting VDAC1 in diabetic cardiomyopathy

We previously established a rat model of diabetic cardiomyopathy (DCM) and found that the expression of lncRNA H19 was significantly downregulated. The present study was designed to investigate the pathogenic role of H19 in the development of DCM. Overexpression of H19 in diabetic rats attenuated ox...

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Detalles Bibliográficos
Autores principales: Li, Xiangquan, Wang, Hao, Yao, Biao, Xu, Weiting, Chen, Jianchang, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087087/
https://www.ncbi.nlm.nih.gov/pubmed/27796346
http://dx.doi.org/10.1038/srep36340