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IKKε inhibits PKC to promote Fascin-dependent actin bundling

Signaling molecules have pleiotropic functions and are activated by various extracellular stimuli. Protein kinase C (PKC) is activated by diverse receptors, and its dysregulation is associated with diseases including cancer. However, how the undesired activation of PKC is prevented during developmen...

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Detalles Bibliográficos
Autores principales: Otani, Tetsuhisa, Ogura, Yosuke, Misaki, Kazuyo, Maeda, Takuya, Kimpara, Akiyo, Yonemura, Shigenobu, Hayashi, Shigeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087637/
https://www.ncbi.nlm.nih.gov/pubmed/27578797
http://dx.doi.org/10.1242/dev.138495