Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells

Harnessing epigenetic regulation is crucial for the efficient and proper differentiation of pluripotent stem cells (PSCs) into desired cell types. Histone H3 lysine 27 trimethylation (H3K27me3) functions as a barrier against cell differentiation through the suppression of developmental gene expressi...

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Detalles Bibliográficos
Autores principales: Akiyama, Tomohiko, Wakabayashi, Shunichi, Soma, Atsumi, Sato, Saeko, Nakatake, Yuhki, Oda, Mayumi, Murakami, Miyako, Sakota, Miki, Chikazawa-Nohtomi, Nana, Ko, Shigeru B. H., Ko, Minoru S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087640/
https://www.ncbi.nlm.nih.gov/pubmed/27802135
http://dx.doi.org/10.1242/dev.139360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087640/
https://www.ncbi.nlm.nih.gov/pubmed/27802135
http://dx.doi.org/10.1242/dev.139360

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