Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay

Dishevelled (DVL) assembles Wnt signalosomes through dynamic head-to-tail polymerisation by means of its DIX domain. It thus transduces Wnt signals to cytoplasmic effectors including β-catenin, to control cell fates during normal development, tissue homeostasis and also in cancer. To date, most func...

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Detalles Bibliográficos
Autores principales: Gammons, Melissa V., Rutherford, Trevor J., Steinhart, Zachary, Angers, Stephane, Bienz, Mariann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087658/
https://www.ncbi.nlm.nih.gov/pubmed/27744318
http://dx.doi.org/10.1242/jcs.195685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087658/
https://www.ncbi.nlm.nih.gov/pubmed/27744318
http://dx.doi.org/10.1242/jcs.195685

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