Drosophila sensory cilia lacking MKS proteins exhibit striking defects in development but only subtle defects in adults

Cilia are conserved organelles that have important motility, sensory and signalling roles. The transition zone (TZ) at the base of the cilium is crucial for cilia function, and defects in several TZ proteins are associated with human congenital ciliopathies such as nephronophthisis (NPHP) and Meckel...

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Detalles Bibliográficos
Autores principales: Pratt, Metta B., Titlow, Joshua S., Davis, Ilan, Barker, Amy R., Dawe, Helen R., Raff, Jordan W., Roque, Helio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087661/
https://www.ncbi.nlm.nih.gov/pubmed/27577095
http://dx.doi.org/10.1242/jcs.194621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087661/
https://www.ncbi.nlm.nih.gov/pubmed/27577095
http://dx.doi.org/10.1242/jcs.194621

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