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Refilins are short-lived Actin-bundling proteins that regulate lamellipodium protrusion dynamics

Refilins (RefilinA and RefilinB) are members of a novel family of Filamin binding proteins that function as molecular switches to conformationally alter the Actin filament network into bundles. We show here that Refilins are extremely labile proteins. An N-terminal PEST/DSG(X)(2-4)S motif mediates u...

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Detalles Bibliográficos
Autores principales: Gay, Olivia, Gilquin, Benoît, Assard, Nicole, Stuelsatz, Pascal, Delphin, Christian, Lachuer, Joël, Gidrol, Xavier, Baudier, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087682/
https://www.ncbi.nlm.nih.gov/pubmed/27744291
http://dx.doi.org/10.1242/bio.019588