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Refilins are short-lived Actin-bundling proteins that regulate lamellipodium protrusion dynamics
Refilins (RefilinA and RefilinB) are members of a novel family of Filamin binding proteins that function as molecular switches to conformationally alter the Actin filament network into bundles. We show here that Refilins are extremely labile proteins. An N-terminal PEST/DSG(X)(2-4)S motif mediates u...
Autores principales: | Gay, Olivia, Gilquin, Benoît, Assard, Nicole, Stuelsatz, Pascal, Delphin, Christian, Lachuer, Joël, Gidrol, Xavier, Baudier, Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087682/ https://www.ncbi.nlm.nih.gov/pubmed/27744291 http://dx.doi.org/10.1242/bio.019588 |
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