The decapping activator Edc3 and the Q/N-rich domain of Lsm4 function together to enhance mRNA stability and alter mRNA decay pathway dependence in Saccharomyces cerevisiae

The rate and regulation of mRNA decay are major elements in the proper control of gene expression. Edc3 and Lsm4 are two decapping activator proteins that have previously been shown to function in the assembly of RNA granules termed P bodies. Here, we show that deletion of edc3, when combined with a...

Descripción completa

Detalles Bibliográficos
Autores principales: Huch, Susanne, Müller, Maren, Muppavarapu, Mridula, Gommlich, Jessie, Balagopal, Vidya, Nissan, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087693/
https://www.ncbi.nlm.nih.gov/pubmed/27543059
http://dx.doi.org/10.1242/bio.020487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087693/
https://www.ncbi.nlm.nih.gov/pubmed/27543059
http://dx.doi.org/10.1242/bio.020487

Ejemplares similares